Something like TetraLibro (four books in one) would be nice. Here is an English translation from the original Italian article http://iit.bloomu.edu/pam/blog/index.cfm/2006/6/22/The-First-TetraLibro-is-Bornsup8482sup
Accommodative Services on our campus uses Kurzweil to scan when possible but it takes someone time to do that. I believe students are now able to buy digital formats of certain texts from the University Bookstore but I'm not sure if they are screen reader friendly.