Don, we did some research at the University of Leicester (details at www.le.ac.uk/duckling) where we issued students doing distance programmes with e-book readers that had been pre-loaded with the course content. Many of the students said they no longer felt the need to print out their course materials, but there were a few people who said they still preferred to work on paper.Some people read the materials on their e-books to get a general overview of the topic, and then printed out the bits that they wanted to read in more detail and annotate by hand. I guess the ideal is to use technologies that give people the choice, which I think e-books do.
Thanks, for this interesting idea, Gabi, and it reminds us that no matter how we design, it is ultimately the reader who will decide how our products will be used. We can persuade people by taking full advantage of multimedia and interactive affordances of e-books, but it doesn't mean people will consume them in the way we intended.
In this way, epubs can be more like "good" literature who had "hidden" Easter eggs like symbolism, allusion, metaphor, etc.