My apologies, but just my two cents ..Better late than never!
Yes, one can DO science without hands... without body, even! well, almost . On reading this point, I immediately thought of Stephen Hawking .
I would put it this way: science needs "brains" perhaps more than hands.
Also, more relevant to this discussion, Stephen Hawking's experience and work could also be as a good case-in-point of extreme how technology may drive us to re-think science.